Stomatológ 2021, 31(2):36-42 | DOI: 10.69658/sto.2021.020

Recurrent aphthous stomatitis as an autoimmune disease

Silvia Timková*, Jana Kluknavská, Eugen Ďurovič, Jozef Minčík
1. stomatologická klinika Univerzitnej nemocnice L. Pasteura a Lekárskej fakulty UPJŠ Košice

In the study, the authors present brief characteristics on RAS (Recurrent Aphthous Stomatitis). Initially, they report that three clinical forms are currently recognized: 1. minor aphthous stomatitis, 2. major aphthous stomatitis that replaces recurrent necrotizing mucous periodontitis, 3. herpetiform ulcers, which are not etiologically related to type 1 or type 2 herpes viruses. Their classification is supported by data in the table below. Then, the authors report on the factors that may come into causation with RAS. In an overview, they provide characteristics and report on epidemiology, causality, local factors, and relationships to a group of herpes viruses, Helicobacter pylori infections, systemic diseases, allergies, immunological factors, tobacco, nutritional deficiencies, clinical and microscopic results in pathogenesis, hereditary factors, drug forms and other factors. In conclusion, the authors point out that RAS is the most common ulcerative lesion of the oral mucosa. It is a long-known disease with unknown aetiology. Currently, it is believed that RAS is an auto-immune disease or immuno-modulatory disorder that does not endanger patients' lives, but may reduce the quality of life in the short term.

Keywords: recurrent aphthous stomatitis, aphthosis minor, aphthosis major

Published: December 15, 2021  Show citation

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Timková S, Kluknavská J, Ďurovič E, Minčík J. Recurrent aphthous stomatitis as an autoimmune disease. Stomatológ. 2021;31(2):36-42. doi: 10.69658/sto.2021.020.
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