Stomatológ 2019, 29(2):56-59 | DOI: 10.69658/sto.2019.023

Side effects of drugs on the periodontium and oral mucosa

Silvia Timková*, Jana Kluknavská, Eugen Ďurovič, Jozef Minčík, Barbora Novotná, Ľuboš Harvan
I. stomatologická klinika LF UPJŠ a UN L. Pasteura, Košice
SKZL - Regionálna komora zubných lekárov - výbor pre vzdelávanie, Košice
Klinika zubního lékařství, Univerzita Palackého Olomouc (ČR)

The continuous development of new drugs and drug forms has undoubtedly a positive role in the treatment of various diseases. However, all drugs have certain adverse or side effects that can affect various systems and also may occur in the oral cavity. These manifestation can be classified according to their localization as periodontium or mucosa affliction in the oral cavity. In the article the authors describe possible manifestations of drugs in the oral cavity as well as the drugs that can cause these changes. Fibrovascular hyperplasia and focal epithelial hyperplasia are also briefly described. Proper classification of drug-induced conditions in the oral cavity is needed, but this classification must be flexible to accommodate new disease states due to the continuous development of science and drug forms.

Keywords: oral mucosa, side effects of drugs

Published: December 15, 2019  Show citation

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Timková S, Kluknavská J, Ďurovič E, Minčík J, Novotná B, Harvan Ľ. Side effects of drugs on the periodontium and oral mucosa. Stomatológ. 2019;29(2):56-59. doi: 10.69658/sto.2019.023.
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    References

    1. ALISON, J., BRUCE, M., B., Ch.B.: Oral Manifestations of Autoimmune and Inflammatory Disease. Medical Derm Society. Mayo Clinic College of Medicine, Rochester, MN. March 14.
    2. AMDOLAH, M., RAHINI, R., RADFAR, M.: Current Opinion on Drug-induced Oral Reactions: A Comprehensive Review. The Journal of Contemporary Dental Practice, Volume 9, No. 3, March 1, 2008. Go to original source...
    3. CHAPPLE, ILC, MEALEY, BL, VAN DYKE, TE. et al. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018 Jun; 89 Suppl 1: S74-S84.
    4. CHI, C., A., BRAD, W., N., KRAYER, W., J. and al.: Oral Manifestations of Systemic Disease. Am Fam Physician. 2010; 82 (11): 1381-1388.
    5. HALLMON, ROSSMANN, A., J.: The role of drugs in the pathogenesis of gingival overgrowth. Periodontology 2000, Vol. 21, 1999, 176-196. Go to original source... Go to PubMed...
    6. SCULLY, C., BAGAN-SEBASTIAN, J., V.: Adverse drug reactions in the orofacial region. Crit Rev Oral Biol Med. 15 (4): 221-240 (2004). Go to original source... Go to PubMed...
    7. SCULLY, C.: Drug effects on salivary glands: dry mouth. Oral Diseases (2003) 9, 165-176. Go to original source... Go to PubMed...
    8. TACK, A., G., ROY, S., ROGERS, H., I. Oral drug reactions.Dermatologic therapy. 15, 2002; 236-250. Go to original source...
    9. TROPHIMUS GNANABAGYAN JAYAKARAN. The Effect of Drugs in the Oral Cavity - A Review./J. Pharm. Sci. & Res. Vol. 6 (2), 2014, 89-96.
    10. VUČIĆEVIĆ BORAS, V. et al.: ADVERSE DRUG REACTIONS IN THE ORAL CAVITY. Acta Clin Croat, Vol. 54, No. 2, 2015.
    11. YUAN, A., WOO, B., S.: Adverse drug events in the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol 2015; 119: 35-47. Go to original source... Go to PubMed...

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